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NIAID Scientists Detail First Structure of a Natural Mammalian Prion

Revealing the near-atomic structure of a chronic wasting disease prion from a deer should help scientists explain how CWD prions spread and become infectious.

The Eyes Have it: A Functional Role for Prion Protein

Answers to what a normal prion protein does could help lead them to develop treatments and disease-prevention measures against human prion diseases, such as Creutzfeldt-Jakob disease, fatal familial insomnia and kuru, as well as animal prion diseases, such as scrapie in sheep and chronic wasting disease in cervids.

Novel Study Model Reveals New Understanding of Fatal Familial Insomnia

Fatal familial insomnia (FFI) is a little-known yet horrific disease in which people die from lack of sleep. In a new study, NIAID scientists developed a cerebral organoid model to study the exact protein mutation that causes FFI.

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